Antimicrobial, Cytotoxic, and Anti-Inflammatory Activities of Pimenta dioica and Rosmarinus officinalis Essential Oils (Record no. 55475)

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control field MX-MdCICY
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control field 20250625164354.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-21415
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Title Antimicrobial, Cytotoxic, and Anti-Inflammatory Activities of Pimenta dioica and Rosmarinus officinalis Essential Oils
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Series statement BioMed Research International. 2019, 1639726, 2019, DOI: 10.1155/2019/1639726
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Summary, etc. Essential oils (EOs) are natural products composed of a mixture of volatile and aromatic compounds extracted from different parts of plants that have shown antimicrobial activities against pathogens. In this study, EOs extracted from Pimenta dioica (Myrtaceae) and Rosmarinus officinalis (Lamiaceae) were assessed for their antimicrobial activities using a panel of pathogenic Gram-positive, Gram-negative, and fungal strains. The antimicrobial activity was measured by the minimal inhibitory concentration required for the growth inhibition of the microorganisms. The cytotoxicity of the EOs was tested ex vivo using the model of human-derived macrophage THP-1 cells. In addition, an inflammatory response was evaluated using the anti-inflammatory cytokine IL-10 and the proinflammatory cytokines IL-6 and TNF-. Results showed that both EOs had antimicrobial activity and different pathogens were exposed to concentrations ranging between 600 and 2000 ?g/mL. In addition, the EOs showed no inflammatory activity when exposed to human macrophages, but a potent anti-inflammatory activity was measured when the oil from Rosmarinus officinalis was exposed to macrophages. This study demonstrates that the use of EOs is an effective alternative for pathogenic bacterial and fungal control, alone or in combination with antibiotic therapy. Moreover, the oil extracted from Rosmarinus officinalis could be used as potent anti-inflammatory agent. © 2019 Ana Cecilia Lorenzo-Leal et al.
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Personal name Lorenzo-Leal A.C.
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Personal name Palou E.
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Personal name López-Malo A.
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Personal name Bach H.
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Uniform Resource Identifier <a href="https://drive.google.com/file/d/1FG-GPDAKUUP8GRKIxcIKLna2kvPtuFEO/view?usp=drive_link">https://drive.google.com/file/d/1FG-GPDAKUUP8GRKIxcIKLna2kvPtuFEO/view?usp=drive_link</a>
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-21415 25.06.2025 25.06.2025 Documentos solicitados