MARC details
| 000 -LEADER |
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| fixed length control field |
02190nam a2200325Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250626080926.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-20422 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
Differentiation of Cinchonine and Cinchonidine Derivatives Through 13C NMR Analysis of the Quinuclidine Ring |
| 490 0# - SERIES STATEMENT |
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| Series statement |
Applied Magnetic Resonance, HTTPS://DOI.ORG/10.1007/S00723-024-01687-3 |
| 500 ## - GENERAL NOTE |
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| General note |
Artículo |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
With a view to developing a procedure for the diferentiation of cinchonine derivatives from cinchonidine derivatives by NMR analysis, experimental data on cinchonine and cinchonidine, after their dissolution in diferent solvents (CDCl3, CD3OD and DMSO-d6), were compared with theoretical data, originating from diferent methodologies: DP4, DP4+, J-DP4 and ANN. Taking into account the lower computational consumption, as well as the greater efciency in diferentiation, the method selected was the trained artifcial neural networks (ANN), which considered only the 13C data from the quinuclidine ring. The method successfully diferentiated derivatives originating from OH group protection in ester and ether forms; replacement of the OH group by F and NH2; insertions of N3, 1H-1,2,3-triazol-1-yl and CH3O groups, linked to the quinoline ring; conversion of the vinyl group to the 1-benzyl-1H-1,2,3-triazol-4-yl; and of hydrogenation, dehydrogenation, and bromination of the vinyl group. In all cases the application of the ANN method succeeded in diferentiation of cinchonine from cinchonidine derivatives. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ARTIFICIAL NEURAL NETWORK METHODS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
COMPUTATIONAL CONSUMPTION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
DIFFERENT SOLVENTS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
GROUP PROTECTION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
NMR ANALYSIS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
OH-GROUPS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
QUINOLINE RINGS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
QUINUCLIDINES |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
VINYL GROUP |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Oliveira, D. F. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Machado, A. R. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Aguilar, M. G. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Viana, A. J. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/15UqPUIGZb3qP_adywRpkoZO8wDZg4HE2/view?usp=drive_link">https://drive.google.com/file/d/15UqPUIGZb3qP_adywRpkoZO8wDZg4HE2/view?usp=drive_link</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
