MARC details
| 000 -LEADER |
| fixed length control field |
03445nam a22004215i 4500 |
| 001 - CONTROL NUMBER |
| control field |
978-0-387-25151-6 |
| 003 - CONTROL NUMBER IDENTIFIER |
| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
| control field |
20250710083932.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
| fixed length control field |
100301s2005 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
| International Standard Book Number |
9780387251516 |
| -- |
99780387251516 |
| 024 7# - OTHER STANDARD IDENTIFIER |
| Standard number or code |
10.1007/b106833 |
| Source of number or code |
doi |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
| Classification number |
572 |
| Edition information |
23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
| Personal name |
Hooper, Nigel M. |
| Relator term |
editor. |
| 245 14 - TITLE STATEMENT |
| Title |
The ADAM Family of Proteases |
| Medium |
[recurso electrónico] / |
| Statement of responsibility, etc. |
edited by Nigel M. Hooper, Uwe Lendeckel. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
| Place of production, publication, distribution, manufacture |
Boston, MA : |
| Name of producer, publisher, distributor, manufacturer |
Springer US, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2005. |
| 300 ## - PHYSICAL DESCRIPTION |
| Extent |
XIX, 344 p. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
| Carrier type term |
recurso en línea |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 490 1# - SERIES STATEMENT |
| Series statement |
Proteases in Biology and Disease ; |
| Volume/sequential designation |
4 |
| 505 0# - FORMATTED CONTENTS NOTE |
| Formatted contents note |
Contributing Authors -- Preface -- Introduction to the ADAM Family, Judith White, Lance Bridges, Douglas DeSimone, Monika Tomczuk and Tyra Wolfsberg -- Studies from ADAM Knockout Mice, Keisuke Hoiruchi and Carl P. Blobel -- ADAM8/MS2/CD156a, Jörg W. Bartsch, Silvia Naus, Andrea Rittger, Uwe Schlomann, Dirk Wildeboer -- ADAM9, Shoichi Ishiura -- ADAM10, Paul Saftig and Dieter Hartmann -- ADAM12, Ulla M. Wewer, Reidar Albrechtsen and Eva Engvall -- Adam13 function in development, Dominique Alfandari, ADAM 17, Joaquín Arribas and Soraya Ruiz-Paz -- ADAM19, Tiebang Kang, Robert G. Newcomer, Yun-Ge Zhao and Qing-Xiang Amy Sang -- ADAM28, Anne M. Fourie -- Mammalian ADAMS with Testis-Specific Or -Predominant Expression, Chunghee Cho -- Overview OF ADAMTS Proteinases and ADAMTS-2, Daniel S. Greenspan and Wei-Man Wang -- ADAMTS-3 AND ADAMTS-14, Carine Le Goff and Suneel S. Apte -- ADAMTS-4 and ADAMTS-5, Anne-Marie Malfait, Micky Tortorella and Elizabeth Arner -- ADAMTS-13, Han-Mou Tsai -- Index. |
| 520 ## - SUMMARY, ETC. |
| Summary, etc. |
The ADAM Family of Proteases provides the first comprehensive review of the roles of ADAMs and the related ADAMTS proteases in biology and disease. Although a few members of the ADAM (a disintegrin and metalloprotease) family have been known for some time, it is only in recent years through advances in genome sequencing that the large size of this family of zinc metalloproteases has become apparent. These proteins have multiple domains including a protease domain and a disintegrin domain. A branch of the family, called ADAMTS, also have thrombospondin-like motifs. The role of ADAMs and ADAMTS members in a diversity of biological processes is gradually coming to light. For example, some ADAMs have critical roles in the ectodomain shedding of membrane proteins including tumour necrosis factor-a, the cell signalling molecule Notch and the Alzheimer's amyloid precursor protein. Other ADAM and ADAMTS family members have key roles to play in sperm function and fertility, collagen processing, development, cardiac hypertrophy and arthritis. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name entry element |
LIFE SCIENCES. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name entry element |
BIOCHEMISTRY. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name entry element |
LIFE SCIENCES. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name entry element |
BIOCHEMISTRY, GENERAL. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Lendeckel, Uwe. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
| Relationship information |
Printed edition: |
| International Standard Book Number |
9780387251493 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
| Uniform title |
Proteases in Biology and Disease ; |
| Volume/sequential designation |
4 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
| Uniform Resource Identifier |
<a href="http://dx.doi.org/10.1007/b106833">http://dx.doi.org/10.1007/b106833</a> |
| Public note |
Ver el texto completo en las instalaciones del CICY |
| 912 ## - |
| -- |
ZDB-2-SBL |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Libros electrónicos |