MARC details
| 000 -LEADER |
|---|
| fixed length control field |
04931nam a22005295i 4500 |
| 001 - CONTROL NUMBER |
|---|
| control field |
978-0-387-33827-9 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20250710083952.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
|---|
| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
100301s2006 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9780387338279 |
| -- |
99780387338279 |
| 024 7# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
10.1007/0-387-33827-6 |
| Source of number or code |
doi |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
614.5999 |
| Edition information |
23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Hatfield, Dolph L. |
| Relator term |
editor. |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Selenium |
| Medium |
[recurso electrónico] : |
| Remainder of title |
Its Molecular Biology and Role in Human Health / |
| Statement of responsibility, etc. |
edited by Dolph L. Hatfield, Marla J. Berry, Vadim N. Gladyshev. |
| 250 ## - EDITION STATEMENT |
|---|
| Edition statement |
Second Edition. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Boston, MA : |
| Name of producer, publisher, distributor, manufacturer |
Springer US, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2006. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XXIV, 420 p. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
|---|
| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
recurso en línea |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
|---|
| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Selenium: A historical perspective -- Selenium: A historical perspective -- Biosynthesis of selenocysteine and its incorporation into protein -- Selenium metabolism in prokaryotes -- Mammalian and other eukaryotic selenocysteine tRNAs -- Evolution of selenocysteine decoding and the key role of selenophosphate synthetase in the pathway of selenium utilization -- SECIS RNAs and K-turn binding proteins. A survey of evolutionary conserved RNA and protein motifs -- SECIS binding proteins and eukaryotic selenoprotein synthesis -- The importance of subcellular localization of SBP2 and EFsec for selenoprotein synthesis -- Selenocysteine biosynthesis and incorporation may require supramolecular complexes -- Selenium-containing proteins -- Selenoproteins and selenoproteomes -- Deletion of selenoprotein P gene in the mouse -- Selenium and methionine sulfoxide reduction -- Selenoprotein W in development and oxidative stress -- The 15-kDa selenoprotein (Sep15): functional analysis and role in cancer -- Regulation of glutathione peroxidase-1 expression -- Selenoproteins of the glutathione system -- New roles of glutathione peroxidase-1 in oxidative stress and diabetes -- Selenoproteins of the thioredoxin system -- Mitochondrial and cytosolic thioredoxin reductase knockout mice -- Selenium, deiodinases and endocrine function -- Biotechnology of selenocysteine -- Selenium and human health -- Selenium, selenoproteins and brain function -- Selenium as a cancer preventive agent -- Peering down the kaleidoscope of thiol proteomics and unfolded protein response in studying the anticancer action of selenium -- Genetic variation among selenoprotein genes and cancer -- Selenium and viral infections -- Role of selenium in HIV/AIDS -- Effects of selenium on immunity and aging -- Selenium and male reproduction -- Mouse models for assessing the role of selenoproteins in health and development -- Drosophila as a tool for studying selenium metabolism and role of selenoproteins -- Selenoproteins in parasites -- Incorporating 'omics' approaches to elucidate the role of selenium and selenoproteins in cancer prevention -- Selenium-induced apoptosis -- Selenoprotein mimics -- Update of human dietary standards for selenium. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Selenium is an essential trace element in the diet of humans and many other life forms. As discussed in this book, selenium plays an important role in preventing certain forms of cancer, heart disease and other cardiovascular and muscle disorders. Evidence points to numerous other health benefits including an indispensable function in development, male reproduction and the immune system. In addition, selenium serves as an antiviral agent and may delay the onset of AIDS in HIV positive patients and delay the aging process. This element occurs primarily in cellular proteins in the form of a novel amino acid selenocysteine. Selenocysteine is the 21st amino acid in the genetic code and is cotranslationally incorporated into protein in response to the codon, UGA. Selenoproteins control redox homeostasis and are involved in variety of cellular pathways. The emphasis of this book is on the current status of the molecular biology of selenium. The importance of this element in human health is also highlighted. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
MEDICINE. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
ONCOLOGY. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
IMMUNOLOGY. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
NEUROSCIENCES. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
NUTRITION. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
METABOLIC DISEASES. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
BIOMEDICINE. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
CANCER RESEARCH. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
IMMUNOLOGY. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
ONCOLOGY. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
NUTRITION. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
METABOLIC DISEASES. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
NEUROSCIENCES. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Berry, Marla J. |
| Relator term |
editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Gladyshev, Vadim N. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9780387338262 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
<a href="http://dx.doi.org/10.1007/0-387-33827-6">http://dx.doi.org/10.1007/0-387-33827-6</a> |
| Public note |
Ver el texto completo en las instalaciones del CICY |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Libros electrónicos |
