Proliferation, cancer, and aging-novel functions of the nucleolar methyltransferase fibrillarin? (Record no. 61952)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01610nam a2200277Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20251009160707.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-21862 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 251009s9999 xx 000 0 und d |
| 245 10 - TITLE STATEMENT | |
| Title | Proliferation, cancer, and aging-novel functions of the nucleolar methyltransferase fibrillarin? |
| 490 0# - SERIES STATEMENT | |
| Series statement | Cell Biol Int 42 (2018) 1463-1466, 2018 |
| 500 ## - GENERAL NOTE | |
| General note | Artículo |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Fibrillarin is an essential nucleolar protein that catalyzes the 2′‐O‐methylation of ribosomal RNAs. Recently, experimental data have begun to accumulate that suggest that fibrillarin can influence various cellular processes, development of pathological processes, and even aging. The exact mechanism by which fibrillarin can influence these processes has not been found, but some experimental data indicate that up‐ or downregulation of fibrillarin can modify the ribosome structure and, thus, causе an alteration in relative efficiency with which various mRNAs are translated. Here, we discuss recent studies on the potential roles of fibrillarin in the regulation of cell proliferation, cancer progression, and aging. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | 20-O-METHYLATION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | AGING |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | CANCER |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | FIBRILLARIN |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | PROLIFERATION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | RIBOSOME HETEROGENEITY |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shubina, M. Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Musinova, Y. R. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sheval, E. V. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1mzPZRyzTLRrflggbcJFWRKyr83-eJhzE/view?usp=drive_link">https://drive.google.com/file/d/1mzPZRyzTLRrflggbcJFWRKyr83-eJhzE/view?usp=drive_link</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 09.10.2025 | B-21862 | 09.10.2025 | 09.10.2025 | Documentos solicitados |