Metabolic flux balancing: basic concepts, scientific and practical use. (Record no. 62039)

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control field MX-MdCICY
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control field 20251009160710.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-21950
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Title Metabolic flux balancing: basic concepts, scientific and practical use.
490 0# - SERIES STATEMENT
Series statement Bio/technology, 12(10), 994-998, 1994.
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General note Artículo
520 3# - SUMMARY, ETC.
Summary, etc. Recently, there has been an increasing interest in stoichiometric analysis of metabolic flux distributions. Flux balance methods only require information about metabolic reaction stoichiometry, metabolic requirements for growth, and the measurement of a few strain-specific parameters. This information determines the domain of stoichiometrically allowable flux distributions that may be taken to define a strain's “metabolic genotype”. Within this domain a single flux distribution is sought based on assumed behavior, such as maximal growth rates. The optimal flux distributions are calculated using linear optimization and may be taken to represent the strain's “metabolic phenotype” under the particular conditions. This flux balance methodology allows the quantitative interpretation of metabolic physiology, gives an interpretation of experimental data, provides a guide to metabolic engineering, enables optimal medium formulation, and provides a method for bioprocess optimization. This spectrum of applications, and its ease of use, makes the metabolic flux balance model a potentially valuable approach for the design and optimization of bioprocesses.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element BACTERIA (MICROORGANISMS)
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CORYNEBACTERIUM GLUTAMICUM
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ESCHERICHIA COLI
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Varma, A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Palsson, B. O.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1dnzn02eJn2AG6SxvBywdZ6kJV_sp--9V/view?usp=drive_link">https://drive.google.com/file/d/1dnzn02eJn2AG6SxvBywdZ6kJV_sp--9V/view?usp=drive_link</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 09.10.2025   B-21950 09.10.2025 09.10.2025 Documentos solicitados