Pioneering NMR-based dereplication for identifying novel quinolone additives in personal care products: A new frontier in public health protection. (Record no. 62055)

MARC details
000 -LEADER
fixed length control field 02093nam a2200313Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20251009160711.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-21967
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 251009s9999 xx 000 0 und d
245 10 - TITLE STATEMENT
Title Pioneering NMR-based dereplication for identifying novel quinolone additives in personal care products: A new frontier in public health protection.
490 0# - SERIES STATEMENT
Series statement Talanta, 285, 127304, 2025.
500 ## - GENERAL NOTE
General note Artículo
520 3# - SUMMARY, ETC.
Summary, etc. Personal care products (PCPs) are often adulterated with antimicrobial agents, such as quinolones, which pose risks to consumer safety and challenge regulatory oversight. Current detection methods rely on standard reference substances and are limited in identifying novel quinolone isomers and structural derivatives. In this study, we present the first use of MixONat, an advanced dereplication tool, combined with 13C NMR spectroscopy to detect illegal quinolone additives in PCPs. Key advancements include the establishment of an in-house quinolone database, innovative sample pretreatment methods, and the integration of these elements to improve the detection of new illegal additives in PCPs. Standard addition experiments in both blank matrices and commercial cosmetics successfully identified new quinolones not included in the database, with effective differentiation of stereoisomers such as ofloxacin and levofloxacin. The proposed approach significantly improves detection efficiency and accuracy, bolstering PCP safety regulations and contributing to public health protection.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PERSONAL CARE PRODUCTS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element NMR DEREPLICATION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element QUINOLONE ADDITIVES
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ILLEGAL ADDITIVES
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MIXONAT
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PUBLIC HEALTH PROTECTION
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Du, X.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Lin, X.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Yuan, R.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Yang, H.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Lu, Y.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Wu, X.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1NW4Lq4OfsmOQFLl-Yze3W4zucxAZ9g2-/view?usp=drive_link">https://drive.google.com/file/d/1NW4Lq4OfsmOQFLl-Yze3W4zucxAZ9g2-/view?usp=drive_link</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
Holdings
Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 09.10.2025   B-21967 09.10.2025 09.10.2025 Documentos solicitados