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Monoclonal antibody manufacturing in transgenic plants - myths and realities

Tipo de material: TextoTextoSeries ; Current Opinion in Biotechnology, 13(6), p.630-635, 2002Trabajos contenidos:
  • Hood, E.E
  • Woodard, S.L
  • Horn, M.E
Tema(s): Recursos en línea: Resumen: The number and types of antibodies expressed in plants has increased steadily since the first reports of this accomplishment in the 1980s, illustrating the versatility of plants as a production system for antibodies. Many recent reviews have detailed the antibody forms that have been derived from plant expression systems. This contribution focuses on the remaining challenges to develop plant-derived therapeutic antibodies into products, and some of the progress that is being made in addressing these challenges. Plants are proving to be a versatile system for the production of antibodies, but some challenges remain
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The number and types of antibodies expressed in plants has increased steadily since the first reports of this accomplishment in the 1980s, illustrating the versatility of plants as a production system for antibodies. Many recent reviews have detailed the antibody forms that have been derived from plant expression systems. This contribution focuses on the remaining challenges to develop plant-derived therapeutic antibodies into products, and some of the progress that is being made in addressing these challenges. Plants are proving to be a versatile system for the production of antibodies, but some challenges remain

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