Antiplasmodial activity of four Kenyan medicinal plants

Tipo de material: Texto

TextoSeries ; Journal of EthnoPharmacology, 56(2), p.133-137, 1997Trabajos contenidos:

Omulokoli, E
Khan, B
Chhabra, S.C

Tema(s):

Recursos en línea:

Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx

Resumen: A preliminary antiplasmodial and phytochemical screening of four Kenyan medicinal plants was carried out. The medicinal plants were extracted and tested for in vitro antiplasmodial activity against chloroquine-sensitive (K67)and chloroquine-resistant (ENT36)strains of Plasmodium falciparum. Out of 16 extracts, 12 were active against ENT36 strain while seven were active against K67 strain, that is, IC50 = 50 g/ml. The most active extracts on both strains were those of leaves of Phyllanthus reticulatus Poir. and Suregada zanzibariensis Baill. (Euphorbiaceae)with IC50 = 10 g/ml. The stembark of Terminalia spinosa Engl. (Combretaceae)and the stems of Dissotis brazzae Cogn. (Melastomataceae)had IC50 = 10 g/ml for strains K67 and ENT36, respectively. A preliminary phytochemical analysis of these plants revealed the presence of different classes of primary and secondary metabolites.

Tags from this library: No tags from this library for this title. Log in to add tags.

Average rating: 0.0 (0 votes)

Holdings
Item type	Current library	Collection	Call number	Status	Date due	Barcode
Documentos solicitados	CICY Documento préstamo interbibliotecario	Ref1	B-6396 (Browse shelf(Opens below))	Available

Browsing CICY shelves, Shelving location: Documento préstamo interbibliotecario, Collection: Ref1 Close shelf browser (Hides shelf browser)

Previous	No cover image available	No cover image available	No cover image available	No cover image available	No cover image available	No cover image available	No cover image available	Next
Previous	B-6393 Isolation of a Previously Unidentified Polysaccharide (MAR-10)from Hyssop officinalis That Exhibits Strong Activity Against Human Immunodeficiency Virus Type 1	B-6394 Evaluation of African medicinal plants for their in vitro trypanocidal activity	B-6395 Antimicrobial study of the resinous exudates and of diterpenoids and flavonoids isolated from some Chilean Pseudognaphalium (Asteraceae)	B-6396 Antiplasmodial activity of four Kenyan medicinal plants	B-6397 Constituents of Picralima nitida display pronounced inhibitory activities against asexual erythrocytic forms of Plasmodium falciparum in vitro	B-6398 Inhibition of HIV activation in latently infected cells by flavonoi compounds	B-6399 Antimalarial activity of extracts and fractions from Bidens pilosa and other Bidens species (Asteraceae)correlated with the presence of acetylene and flavonoid compounds	Next

A preliminary antiplasmodial and phytochemical screening of four Kenyan medicinal plants was carried out. The medicinal plants were extracted and tested for in vitro antiplasmodial activity against chloroquine-sensitive (K67)and chloroquine-resistant (ENT36)strains of Plasmodium falciparum. Out of 16 extracts, 12 were active against ENT36 strain while seven were active against K67 strain, that is, IC50 = 50 g/ml. The most active extracts on both strains were those of leaves of Phyllanthus reticulatus Poir. and Suregada zanzibariensis Baill. (Euphorbiaceae)with IC50 = 10 g/ml. The stembark of Terminalia spinosa Engl. (Combretaceae)and the stems of Dissotis brazzae Cogn. (Melastomataceae)had IC50 = 10 g/ml for strains K67 and ENT36, respectively. A preliminary phytochemical analysis of these plants revealed the presence of different classes of primary and secondary metabolites.

There are no comments on this title.

to post a comment.