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Cytotoxic activity of selected plants used as antitumorals in Mexican traditional medicine

Tipo de material: TextoTextoSeries ; Journal of EthnoPharmacology, 593(3), p.173-177, 1998Trabajos contenidos:
  • Popoca, J
  • Aguilar, A
  • Alonso, A
  • Villarreal, M.L
Tema(s): Recursos en línea: Resumen: Crude extracts from nine plants widely used in Mexican traditional medicine for the treatment of cancer have been subjected to a bioscreening study to detect cytotoxic activity against human tumor cells. Three different extracts (petroleum ether, ethylacetate, and methanol)from each plant species, were tested towards KB, HCT-15 COLADCAR and UISO-SQC-1 cell cultures. The results showed that three plants Colubrina macrocarpa (Cav.)Don (Rhamnaceae), Acacia pennatula (Schltdl. and Cham.)Benth (Leguminosae)and Hemiangium excelsum (HBK.)Smith (Hippocrateaceae), exhibited important cytotoxic activity showing a certain degree of selectivity against the tested cells in culture.
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Crude extracts from nine plants widely used in Mexican traditional medicine for the treatment of cancer have been subjected to a bioscreening study to detect cytotoxic activity against human tumor cells. Three different extracts (petroleum ether, ethylacetate, and methanol)from each plant species, were tested towards KB, HCT-15 COLADCAR and UISO-SQC-1 cell cultures. The results showed that three plants Colubrina macrocarpa (Cav.)Don (Rhamnaceae), Acacia pennatula (Schltdl. and Cham.)Benth (Leguminosae)and Hemiangium excelsum (HBK.)Smith (Hippocrateaceae), exhibited important cytotoxic activity showing a certain degree of selectivity against the tested cells in culture.

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