Screening for highly active Ë-lactam antibiotics against Agrobacterium tumefaciens

Tipo de material: Texto

TextoSeries ; Arch. of MicroBiology, 181(4), p.331-336, 2004Trabajos contenidos:

Ogawa, Y
Mii, M

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Resumen: inhibitory concentrations (MICs)and minimum bactericidal concentrations (MBCs), of 12 â-lactam antibiotics against Agrobacterium tumefaciens strains LBA4404 and EHA101 were examined, in order to identify antibiotics effective in eliminating the bacteria in Agrobacteriummediated plant genetic transformation. The antibacterial activities of â-lactams tested against strain EHA101 were equal to or less than those tested against strain LBA4404. Cefotaxime, cefbuperazone, and meropenem had high activities against strain LBA4404 (MBC <1 mg l-1). Against strain EHA101, however, only meropenem showed activity comparable to that against strain LBA4404. The production of â-lactamase was observed only in strain EHA101.

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inhibitory concentrations (MICs)and minimum bactericidal concentrations (MBCs), of 12 â-lactam antibiotics against Agrobacterium tumefaciens strains LBA4404 and EHA101 were examined, in order to identify antibiotics effective in eliminating the bacteria in Agrobacteriummediated plant genetic transformation. The antibacterial activities of â-lactams tested against strain EHA101 were equal to or less than those tested against strain LBA4404. Cefotaxime, cefbuperazone, and meropenem had high activities against strain LBA4404 (MBC <1 mg l-1). Against strain EHA101, however, only meropenem showed activity comparable to that against strain LBA4404. The production of â-lactamase was observed only in strain EHA101.

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