Endothelialization of Microporous YIGSR/PEG-Modified Polyurethaneurea

Tipo de material: Texto

TextoSeries ; Tissue Engineering, 11(7-8), p.1133-1140, 2005Trabajos contenidos:

Ho-Wook Jun
West, J.L

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Resumen: Bioactive polyurethaneurea modified with polyethylene glycol (PEG)and the endothelial cell-adhesive peptide YIGSR was synthesized and fabricated into microporous scaffolds. This material has shown appropriate mechanical properties for vascular graft applications, resists platelet adhesion, and promotes endothelialization. In the current study, microporous scaffolds were formed by a gasfoaming and salt-leaching method. The scaffolds showed highly interconnected open pores throughout the matrices, with porosity of approximately 78

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Bioactive polyurethaneurea modified with polyethylene glycol (PEG)and the endothelial cell-adhesive peptide YIGSR was synthesized and fabricated into microporous scaffolds. This material has shown appropriate mechanical properties for vascular graft applications, resists platelet adhesion, and promotes endothelialization. In the current study, microporous scaffolds were formed by a gasfoaming and salt-leaching method. The scaffolds showed highly interconnected open pores throughout the matrices, with porosity of approximately 78

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