Azadirachtin, a scientific gold mine

Tipo de material: Texto

TextoSeries ; Bioorganic & Medicinal Chemistry, 17(2), p.4096-4105, 2009Trabajos contenidos:

Morgan, E.D

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Resumen: Azadirachtin is a highly interesting compound both for its chemical structure, which required 18 years to solve, and its synthesis, which required another 22 years, and for its biological properties as a feeding deterrent for many insects and a growth disruptant for most insects and many other arthropods. Its mode of action, structure-activity relationships, and its biosynthesis still require much research. A valuable natural pesticide, it has very low toxicity for vertebrates, and yet it has still not achieved a prominent place among pesticides and in many countries it is not yet licensed for use. An attempt is made to understand its failure to capture a larger market, 40 years after its discovery.

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Documentos solicitados	CICY Documento préstamo interbibliotecario	Ref1	B-10608 (Browse shelf(Opens below))	Available

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Previous	B-10605 Morphological, thermal and rheological properties of starches from different botanical sources	B-10606 Synthesis of Azadirachtin: A Long but Successful Journey	B-10607 Influence of gas components on removal of SO2 from flue gas in the semidry FGD process with a powder±particle spouted bed	B-10608 Azadirachtin, a scientific gold mine	B-10609 Statistical elicitor optimization studies for the enhancement of azadirachtin production in bioreactor Azadirachta indica cell cultivation	B-1061 Process for preparing composite sheet material	B-10610 Comparative Study of the Retrogradation of Intermediate Water Content Waxy Maize, Wheat, and Potato Starches	Next

Azadirachtin is a highly interesting compound both for its chemical structure, which required 18 years to solve, and its synthesis, which required another 22 years, and for its biological properties as a feeding deterrent for many insects and a growth disruptant for most insects and many other arthropods. Its mode of action, structure-activity relationships, and its biosynthesis still require much research. A valuable natural pesticide, it has very low toxicity for vertebrates, and yet it has still not achieved a prominent place among pesticides and in many countries it is not yet licensed for use. An attempt is made to understand its failure to capture a larger market, 40 years after its discovery.

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