Application of Polyhydroxyalkanoates Nanoparticles as Intracellular Sustained Drug-Release Vectors
Tipo de material:
TextoSeries ; Journal of BioMaterials Science, 21(1), p.127-140, 2010Trabajos contenidos: - Xiong, Y
- Yao, Y
- Zhan, X
- Chen, G
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CICY Documento préstamo interbibliotecario | Ref1 | B-11867 (Browse shelf(Opens below)) | Available |
Polyhydroxybutyrate (PHB), co-polyesters of 3-hydroxybutyrate and 3-hydroxyhexanoate (PHBHHx), and polylactic acid (PLA)were used to prepare nanoparticles with average sizes of 160, 250 and 150 nm, respectively. A lipid-soluble colorant, rhodamine B isothiocyanate (RBITC), was employed to study drug-release behaviors from these nanoparticles. A high RBITC drug-loading efficiency of over 75
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