Liquid Chromatography-Mass Spectrometry-based Quantitative Proteomics

Tipo de material: Texto

TextoSeries ; The Journal of Biological Chemistry, 286, p.25443-25449, 2011Trabajos contenidos:

Fang Xie
Tao Liu
Wei-Jun Qian
Petyuk, V.A
Smith, R.D

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Resumen: LC-MS-based quantitative proteomics has become increasingly applied to a wide range of biological applications due to growing capabilities for broad proteome coverage and good accuracy and precision in quantification. Herein, we review the current LC-MS-based quantification methods with respect to their advantages and limitations and highlight their potential applications.

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LC-MS-based quantitative proteomics has become increasingly applied to a wide range of biological applications due to growing capabilities for broad proteome coverage and good accuracy and precision in quantification. Herein, we review the current LC-MS-based quantification methods with respect to their advantages and limitations and highlight their potential applications.

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