Chromatin in pluripotent embryonic stem cells and differentiation

Tipo de material: Texto

TextoSeries ; Nature Reviews Molecular Cell Biology, 7, p.540-546, 2006Trabajos contenidos:

Meshorer, E
Misteli, T

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Resumen: Embryonic stem (ES)cells are unique in that they are pluripotent and have the ability to self-renew. The molecular mechanisms that underlie these two fundamental properties are largely unknown. We discuss how unique properties of chromatin in ES cells contribute to the maintenance of pluripotency and the determination of differentiation properties.

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Embryonic stem (ES)cells are unique in that they are pluripotent and have the ability to self-renew. The molecular mechanisms that underlie these two fundamental properties are largely unknown. We discuss how unique properties of chromatin in ES cells contribute to the maintenance of pluripotency and the determination of differentiation properties.

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