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Pinocembrine: A bioactive flavanone from Teloxys graveolens

Tipo de material: TextoTextoSeries ; Journal of EthnoPharmacology, 31(3), p.383-389, 1991Trabajos contenidos:
  • Del Rayo Camacho, M
  • Sanchez, B
  • Quiroz, H
  • Contreras, J.L
  • Mata, R
Tema(s): Recursos en línea: Resumen: Bioactivity directed fractionation of the acetone extract of Teloxys graveolens (Willd.)Weber (Chenopodiaceae), using the brine shrimp lethality test, led to the isolation of 5,7-dihydroxyflavanone (pinocembrine)(lc50 = 4.25 µg/ml)as the only active compound. Pinocembrine also exhibited fasciolicide, ovicide and larvicide activities on newly excysted Fasciola hepatica, on infective eggs of Ascaridi galli and on stage three larvae of Stomoxys calcitrans, respectively.
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Bioactivity directed fractionation of the acetone extract of Teloxys graveolens (Willd.)Weber (Chenopodiaceae), using the brine shrimp lethality test, led to the isolation of 5,7-dihydroxyflavanone (pinocembrine)(lc50 = 4.25 µg/ml)as the only active compound. Pinocembrine also exhibited fasciolicide, ovicide and larvicide activities on newly excysted Fasciola hepatica, on infective eggs of Ascaridi galli and on stage three larvae of Stomoxys calcitrans, respectively.

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