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Bioactive luteoloside produced by Myroides odoratimimus, solvent-tolerant bacterium form the rhizosphere of Lonicera japonica.

Tipo de material: TextoTextoSeries ; Natural Product Research, 33(24), p.3559-3562, 2019Trabajos contenidos:
  • Zhao, Y. X
  • Wang, J. J
  • Zhang, L
  • Zhang, S
  • Su, S. L
  • Duan, J. A
  • Xu, S. K
Tema(s): Recursos en línea: Resumen: Luteoloside (luteolin-7-O-glucoside), the biomarker of Lonicera japonica, was efficiently bio-synthetized from its cheaper precursor luteolin. The structure of luteoloside was characterized by LC-MS and NMR analyses. Compared to the significant inhibitory effect of luteolin on human hepatocyte cell line LO2 at high doses, luteoloside did not show obvious cytotoxic effects at any test dose. Moreover, luteoloside exhibited obvious promotive effects on human hepatocyte cells, suggesting a potential application in hepatoprotective therapies.
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Documentos solicitados Documentos solicitados CICY Documento préstamo interbibliotecario Ref1 B-18040 (Browse shelf(Opens below)) Available

Luteoloside (luteolin-7-O-glucoside), the biomarker of Lonicera japonica, was efficiently bio-synthetized from its cheaper precursor luteolin. The structure of luteoloside was characterized by LC-MS and NMR analyses. Compared to the significant inhibitory effect of luteolin on human hepatocyte cell line LO2 at high doses, luteoloside did not show obvious cytotoxic effects at any test dose. Moreover, luteoloside exhibited obvious promotive effects on human hepatocyte cells, suggesting a potential application in hepatoprotective therapies.

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