Surface modification of metallic bone implants-Polymer and polymer-assisted coating for bone in-growth

Tipo de material: Texto

TextoSeries ; Fundamental BioMaterials: Metals, 14, p.299-321, 2018Trabajos contenidos:

Adhikari, J
Saha, P
Sinha, A

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Resumen: Metallic implants as a load bearing component are widely selected for orthopedic prosthesis due to their superiority over traditional ceramic and polymeric biomaterials. Metal-based orthopedic implants have undergone a multitude of manufacturing and surface modification techniques for enhancement of biological activities within the host site. Polymeric coatings being biocompatible in nature facilitates biological fixation of metallic implants with native extracellular matrix. Polymer and polymer-assisted coating on the metallic implants promotes the process of osseointegration while fixation related infections get reduced with these coatings. A coating enhances cell material interaction and provides structural support to the newly formed tissues. Corrosion resistance of biodegradable metallic implants (such as Mg and its alloys)can also be increased by preventing implants exposure from the body fluid with a shielding layer fabricated with suitable polymer coatings. Porous structure of the coating is an ideal condition as cells proliferate through the interconnecting porosities

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Metallic implants as a load bearing component are widely selected for orthopedic prosthesis due to their superiority over traditional ceramic and polymeric biomaterials. Metal-based orthopedic implants have undergone a multitude of manufacturing and surface modification techniques for enhancement of biological activities within the host site. Polymeric coatings being biocompatible in nature facilitates biological fixation of metallic implants with native extracellular matrix. Polymer and polymer-assisted coating on the metallic implants promotes the process of osseointegration while fixation related infections get reduced with these coatings. A coating enhances cell material interaction and provides structural support to the newly formed tissues. Corrosion resistance of biodegradable metallic implants (such as Mg and its alloys)can also be increased by preventing implants exposure from the body fluid with a shielding layer fabricated with suitable polymer coatings. Porous structure of the coating is an ideal condition as cells proliferate through the interconnecting porosities

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