Image from Google Jackets

The Link Between Inflammation and Cancer [recurso electrónico] : Wounds that do not heal / edited by Angus G. Dalgleish, Burkhard Haefner.

Por: Colaborador(es): Tipo de material: TextoTextoSeries Cancer Treatment and Research ; 130Editor: Boston, MA : Springer US, 2006Descripción: XII, 254 p. online resourceTipo de contenido:
  • text
Tipo de medio:
  • computer
Tipo de soporte:
  • recurso en línea
ISBN:
  • 9780387262833
  • 99780387262833
Tema(s): Formatos físicos adicionales: Printed edition:: Sin títuloClasificación CDD:
  • 616.994 23
Recursos en línea:
Contenidos:
Foreword -- Inflammation and Cancer: The role of the immune response and angiogenesis -- Chronic Inflammation and Pathogenesis of GI and Pancreatic Cancers -- Cytokines, NF-kB, Microenvironment, Intestinal Inflammation and Cancer -- Regulation of NF-kB Transcriptional Activity -- The Role of Immune Cells in the Tumor Microenvironment -- Tumor-Microenvironment Interactions: The Selectin-Selectin Ligand Axis in Tumor-Endothelium Cross Talk -- CD95L/FasL and Trail in Tumour Surveillance and Cancer Therapy -- Infection & Neoplastic Growth 101: The required reading for microbial pathogens aspiring to cause cancer -- Cytokines as Mediators and Targets for Cancer Cachexia -- Targeting NF-kB in Anticancer Adjunctive Chemotherapy -- Index.
En: Springer eBooksResumen: The transcription factor NF-kB has long been known to play a central role in the immune system by regulating the expression of key genes. Moreover, activation of this transcription factor helps a wide variety of cell types survive damage induced by pro-apoptotic stimuli. Owing to its critical role in the regulation of pro-inflammatory genes, NF-kB has long been regarded as a promising target for the discovery of anti-inflammatory drugs. More recently, NF-kB has emerged as a major culprit in a variety of human cancers mainly due to its ability to protect transformed cells from apoptosis. This finding should not have come as a surprise since there exists a link between inflammation and many types of cancer which was already suggested by Galen and later demonstrated by Virchow. This link, of crucial importance for the design of novel strategies for cancer treatment, is the topic of this book. Series Editor Cover Comments: "Inflammation is a known risk factor for a number of cancers. In this text, experts discuss the pathophysiology and molecular alterations that link these two processes. Potential therapeutics and preventive strategies are discussed." Steven T. Rosen, M.D. Series Editor
Tags from this library: No tags from this library for this title. Log in to add tags.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Collection Call number Status Date due Barcode
Libros electrónicos Libros electrónicos CICY Libro electrónico Libro electrónico 616.994 (Browse shelf(Opens below)) Available

Foreword -- Inflammation and Cancer: The role of the immune response and angiogenesis -- Chronic Inflammation and Pathogenesis of GI and Pancreatic Cancers -- Cytokines, NF-kB, Microenvironment, Intestinal Inflammation and Cancer -- Regulation of NF-kB Transcriptional Activity -- The Role of Immune Cells in the Tumor Microenvironment -- Tumor-Microenvironment Interactions: The Selectin-Selectin Ligand Axis in Tumor-Endothelium Cross Talk -- CD95L/FasL and Trail in Tumour Surveillance and Cancer Therapy -- Infection & Neoplastic Growth 101: The required reading for microbial pathogens aspiring to cause cancer -- Cytokines as Mediators and Targets for Cancer Cachexia -- Targeting NF-kB in Anticancer Adjunctive Chemotherapy -- Index.

The transcription factor NF-kB has long been known to play a central role in the immune system by regulating the expression of key genes. Moreover, activation of this transcription factor helps a wide variety of cell types survive damage induced by pro-apoptotic stimuli. Owing to its critical role in the regulation of pro-inflammatory genes, NF-kB has long been regarded as a promising target for the discovery of anti-inflammatory drugs. More recently, NF-kB has emerged as a major culprit in a variety of human cancers mainly due to its ability to protect transformed cells from apoptosis. This finding should not have come as a surprise since there exists a link between inflammation and many types of cancer which was already suggested by Galen and later demonstrated by Virchow. This link, of crucial importance for the design of novel strategies for cancer treatment, is the topic of this book. Series Editor Cover Comments: "Inflammation is a known risk factor for a number of cancers. In this text, experts discuss the pathophysiology and molecular alterations that link these two processes. Potential therapeutics and preventive strategies are discussed." Steven T. Rosen, M.D. Series Editor

There are no comments on this title.

to post a comment.