cCMP and cUMP come into the spotlight, finally

Tipo de material: Texto

TextoSeries Trends in Biochemical Sciences, 47(6), p.461-463, 2022Trabajos contenidos:

Seifert, R.;Schirmer, B

Tema(s):

UMP COME INTO THE SPOTLIGHT, FINALLY

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Resumen: cCMP and cUMP have been identified in numerous biological systems and proposed to serve as second messengers. However, this proposal remained controversial because of the base-promiscuity of generators, effectors, phosphodiesterases, and bacterial toxins. With the identification of specific cytidylyl and uridylyl cyclases, cCMP and cUMP research enters a new era.

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Artículo

cCMP and cUMP have been identified in numerous biological systems and proposed to serve as second messengers. However, this proposal remained controversial because of the base-promiscuity of generators, effectors, phosphodiesterases, and bacterial toxins. With the identification of specific cytidylyl and uridylyl cyclases, cCMP and cUMP research enters a new era.

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