Yeast mutants pleotropically impaired in the regulation of the two glutamate dehydrogenases. 

 -  BioChemical and Biophysical Research Communcations, 53(2), p.367-371, 1973 .
<br/><br/> Two different yeast mutant strains are described in which the pattern of regulation of the glutamate dehydrogenases (GDHase)are pleitropically altered. Both mutants have more than a 20 fold derepreased level of the catabolic GDHase while the level of the anabolic enzyme is three to four fold lower than that of the wild type strain. Data are reported which indicated that the change in the anabolic enzyme in the more significant one.