Use of structural information in drug design 

 -  Current Opinion in Structural Biology, 2(2), p.202-210, 1992 .
<br/><br/> Modern drug design increasingly relies on structural information for the improvement of in vitro potency. Recently, these methods have been used to optimize in vitro properties as well. Barries to the sucessful integration of these technologies within the drug industry seem to be largely cultural rather than scientific.