TY  - BOOK
AU  - Jiménez,A.
AU  - Meckes,M.
AU  - Alvarez,V.
AU  - Torres,J.
AU  - Parra,R.
TI  - Secondary Metabolites from Chamaedora tepejilote (Palmae)are Active against Mycobacterium tuberculosis
KW  - CHAMAEDORA TEPEJILOTE
KW  - PALMAE
KW  - BIOASSAY-GUIDED ISOLATION
KW  - ANTIMYCOBACTERIAL COMPOUNDS
KW  - TRITERPENOIDS
KW  - URSOLIC ACID
KW  - SQUALENE
N2  - Due to the emergence of multi-drug resistant Mycobacterium tuberculosis strains, there is an urgent need to search for new antimycobacterial drugs. The present work describes the bioactivity-guided fractionation of Chamaedora tepejilote hexane extract which led to the isolation and the characterization of squalene, farnesol, methylic ester of hexadecanoic acid, â -sitosterol and ursolic acid. Activity against Mycobacterium tuberculosis H37Rv, determined by radiorespirometric Bactec assay, showed ursolic acid, squalene and farnesol to produce a M. tuberculosis growth inhibition of 99
UR  - https://drive.google.com/file/d/1ovbGf7UVJn4XtrvTFAUNz9jEYXG2rJYC/view?usp=drivesdk
ER  -