Pericardial substitutes were prepared from stable and degradable segmented polyurethanes and/or polyurethane/polyhydroxybutyratec omposites. Polyurethane membranes implanted as pericardial substitute in the rabbit, did not activate adhesion and epicardial reaction over 3 months. Polyurethane/polyhydroxybutyratem embranesi nducedm inimala dhesiono r epicardial reaction, yet stimulated the growth of epithelium on the polymeric substrate and reduced the incidence of infection.
POLYURETHANES POLYHYDROXYBUTYRATE MEDICAL APPLICATION PERICARDIAL SUBSTITUTE ADHESION