Aluminium cycling in the soil-plant-animal-human continuum 

 -  BioMetals, 17(6), p.669-689, 2004 .
<br/><br/> A critical review of the literature on Al toxicity in plants, animals and humans reveals a similar mode of Al action in all living organisms, namely interference with the secondary messenger system (phosphoinositide and cytosolic Ca2+ signalling pathways)and enhanced production of reactive oxygen species resulting in oxidative stress. Aluminium uptake by plants is relatively quick (across the intact plasma membrane in < 30 min and across the tonoplast in < 1 h), despite huge proportion of Al being bound in the cell wall. Aluminium absorption in the animal/human digestive system is low (only about 0.1