TY  - BOOK
AU  - Bulatovic,V.M.
AU  - Wengenack,N.L.
AU  - Uhl,J.R.
AU  - Hall,L.
AU  - Roberts,G.D.
AU  - Cockerill,F.R.
AU  - Rusnak,F.
TI  - Oxidative Stress Increases Susceptibility of Mycobacterium tuberculosis to Isoniazid
N2  - Isoniazid is a first-line antibiotic used in the treatment of infections caused by Mycobacterium tuberculosis. Isoniazid is a prodrug requiring oxidative activation by the catalase-peroxidase hemoprotein, KatG. Resistance to isoniazid can be obtained by point mutations in the katG gene, with one of the most common being a threonine-for-serine substitution at position 315 (S315T). The S315T mutation is found in more than 50
UR  - https://drive.google.com/file/d/1KqQfDxUEbThpLyIw2OfDv9WtWoFkd7wY/view?usp=drivesdk
ER  -