TY  - BOOK
AU  - Häberli,A.
AU  - Pfander,H.
TI  - Synthesis of Bixin and Three Minor Carotenoids from Annatto (Bixa orellana)
N2  - The three apocarotenoids methyl (9Z)-8'-oxo-6,8'-diapocaroten-6-oate (2), methyl (9Z)-10'-oxo-6,10'- diapocaroten-6-oate (4), and methyl (9Z)-14'-oxo-6,14'-diapocaroten-6-oate (5), recently isolated from annatto, were synthesized. The key step of all three syntheses was the Wittig reaction of the (Z)-terminus 6 with the phosphonium salts 15, 18, and 24, carrying the polyene chain. Bixin (1)was synthesized from 2 in a Horner-Emmons reaction
UR  - https://drive.google.com/file/d/1oqADJGiJKYhB0JCn6Y8zNDhDtzTaNZOO/view?usp=drivesdk
ER  -