TY  - BOOK
AU  - Nes,W.D.
AU  - Le,P.H.
AU  - Berg,L.R.
AU  - Patterson,G.W.
AU  - Kerwin,J.L.
TI  - A comparison of cycloartenol and lanosterol biosynthesis and metabolism by the Oomycetes
KW  - OOMYCETES
KW  - SQUALENE-OXIDE
KW  - CYCLOARTENOL
KW  - LANOSTEROL
KW  - STEROL METABOLISM
N2  - Representative members in each of the four orders of Oomycetes (Phytophthora cactorum, Peronosporales; Lagenidium callineetes, L.giganteum, Lagenidiales; Saprolegnia ferax, Saprolegniales; Apodaehylella completa, Leptomitales)have been examined for their ability to synthesize and polycyclize squalene-oxide (SO)to a tetracyclic product and to differentiate between cycloartenol and lanosterol metabolism to sterols. P. eactorum and L. giganteum failed to synthesize or metabolize SO, cycloartenol or lanosterol. While the other three fungi synthesized sterols via SO and lanosterol, a minor metabolism of added cycloartenol to the 4,4-desmethyl-14e-methylcyclosteroid dehydropollinastanol was observed
UR  - https://drive.google.com/file/d/1sYgSCZ2-z_pPHXjqnFdOHubpY3M0Ws-_/view?usp=drivesdk
ER  -