TY - BOOK AU - Koussevitzky,S. AU - Nott,A. AU - Mockler,T.C. AU - Hong,F. TI - Signals from Chloroplasts Converge to Regulate Nuclear Gene Expression N2 - Plastid-to-nucleus retrograde signaling coordinates nuclear gene expression with chloroplast function and is essential for the photoautotrophic life-style of plants. Three retrograde signals have been described, but little is known of their signaling pathways. We show here that GUN1, a chloroplast-localized pentatricopeptide-repeat protein, and ABI4, an Apetala 2 (AP2)-type transcription factor, are common to all three pathways. ABI4 binds the promoter of a retrograde-regulated gene through a conserved motif found in close proximity to a light-regulatory element. We propose a model in which multiple indicators of aberrant plastid function in Arabidopsis are integrated upstream of GUN1 within plastids, which leads to ABI4- mediated repression of nuclear-encoded genes UR - https://drive.google.com/file/d/14R7H3nDblW-omADLkrAUdl6Xw34QFrep/view?usp=drivesdk ER -