Isolation of Leishmanicidal Triterpenes and Lignans from the Amazonian Liana Doliocarpus dentatus (Dilleniaceae) 

 -  Phytotherapy Research, 10(1), p.1-4, 1996 .
<br/><br/> The in uitro antileishmanial activity of triterpenes and lignans of an Amazonian medicinal plant, Doliocarpus dentutus (Aublet)Standley, is reported for the first time against amastigotes of Leishmania amazonensis. Terpenes, for example, betulinic acid, betulin and betulinaldehyde were isolated by bioassay-linked extraction. The lignans were characterized as (+)pinoresinol, (+)medioresinol and (-)lirioresinol B. 
<br/><br/><label>Subjects--Topical Terms: </label><br/>DOLIOCARPUS DENTATUS<br/>BETULIN ALDEHYDE<br/>(+)MEDIORESINO