TY  - BOOK
AU  - Nam,Y.S.
AU  - Yoon,J.J.
AU  - Park,T.G.
TI  - A Novel Fabrication Method of Macroporous Biodegradable Polymer Scaffolds Using Gas Foaming Salt as a Porogen Additive
KW  - BIODEGRADABLE POLYMERS
KW  - POLY(L-LACTIC ACID)
KW  - SCAFFOLDS
KW  - TISSUE ENGINEERING
KW  - AMMONIUM CARBONATE
N2  - Highly open porous biodegradable poly(L-lactic acid)[PLLA]scaffolds for tissue regeneration were fabricated by using ammonium bicarbonate as an efficient gas foaming agent as well as a particulate porogen salt. A binary mixture of PLLA-solvent gel containing dispersed ammonium bicarbonate salt particles, which became a paste state, was cast in a mold and subsequently immersed in a hot water solution to permit the evolution of ammonia and carbon dioxide within the solidifying polymer matrix. This resulted in the expansion of pores within the polymer matrix to a great extent, leading to well interconnected macroporous scaffolds having mean pore diameters of around 300-400 mm, ideal for high-density cell seeding. Rat hepatocytes seeded into the scaffolds exhibited about 95
UR  - https://drive.google.com/file/d/1wTAyH6URIylvVr6koKOKF_c0qVVBQ2yN/view?usp=drivesdk
ER  -