TY - BOOK AU - Eggert,C. AU - Temp,U. AU - Dean,J.F.D. AU - Eriksson,K.E. TI - A fungal metabolite mediates degradation of non-phenolic lignin structures and synthetic lignin by laccase KW - LIGNIN DEGRADATION KW - WHITE-ROT; CINNABARINIC ACID KW - 3-HYDROXYANTHRANILATE KW - REDOX MEDIATOR KW - PYCNOPORUS CINNABARINUS N2 - Lignin peroxidase is generally considered to be a primary catalyst for oxidative depolymerization of fignin by white-rot fungi. However, some white-rot fungi lack lignin peroxidase. Instead, many produce laccase, even though the redox potentials of known laccases are too low to directly oxidize the non-phenolic components of lignin. Pycnoporus cinnabarinus is one example of a laccase-producing fungus that degrades lignin very efficiently. To overcome the redox potential barrier, P. cinnabarinus produces a metabolite, 3-hydroxyanthranilate that can mediate the oxidation of nowphenolic substrates by laccase. This is the first description of how laccase might function in a biological system for the complete depolymerization of lignin UR - https://drive.google.com/file/d/1UztsdOkdqDNLYrAXPAW8pAN_nDy8ccqD/view?usp=drivesdk ER -