Synthesis of hydrolytically stable low elastic modulus polyurethane-urea for biomedical applications 

 -  Polymer International, 49(1), p.88-92, 2000 .
<br/><br/> Polyurethane-urea without ether linkages was synthesised using dicyclohexyl-methane diisocyanate (SMDI), hydroxy-terminated polybutadiene (HTPBD)andm-phenylenediamine (PDA). The hydrolytic stability of this polymer was investigated under in vitro conditions using Ringer's solution and phosphate-buffered saline, and the stability of candidate polyurethane-urea polymers was compared with that of polyurethane prepared with SMDI, HTPBD and 1,4-butanediol [BD]. The change of tensile properties, hardness and surface properties in the aged polymer is signi®cant for polyurethane when compared with those of polyurethane-urea polymer. The in vitro study revealed possible applications of polyurethane-urea for long-term biomedical applications. 
<br/><br/><label>Subjects--Topical Terms: </label><br/>LOW ELASTIC MODULUS<br/>POLYURETHANE-UREA<br/>HYDROLYTIC STABILITY<br/>BIOMEDICAL APPLICATIONS