Poly(L-lactide)PLLA materials with various porosity in the range of 5 to 300 ~tm were produced by crystallization of the polymer in presence of low molecular weight additives from solution in good solvents, followed by the diluent extraction. For the concentration of diluent in PLLA in the range of 10 to 50 per cent by weight, the pore size increased with increasing concentration of additive, while the additive was easily extracted from the polymer. For the concentration of additive in PLLA in the range of 60 to 80 per cent by weight, the pore size increased or/and decreased with increasing concentration of the additive, while the latter was hardly extractable from the polymer. Porous, resorbable tubes or rods of various diameter well accepted by living organism were produced by this method. Tracheal prostheses, pins Or porous reservoirs made from PLLA or modified porous PLLA could be some of many potential application of these materials.
POLYLACTIDE POROUS BIOMATERIALS MEDICAL APPLICATION BIODEGRADABLE SURGICAL IMPLANTS RESERVOIRS FOR DRUG DELIVERY