TY  - BOOK
AU  - Olejniczak,T.
AU  - Gawronski,J.
AU  - Wawrzenczyk,C.
TI  - Lactones. 6. Microbial lactonization of gamma,delta-epoxy esters
KW  - TERPENOID LACTONES
KW  - BIOCATALYSTS
KW  - SHARPLESS EPOXIDATION
KW  - MICROORGANISMS
KW  - RHODOTORULA RUBRA
KW  - BOTRYTIS CINEREA
KW  - FUSARIUM SEMITECTUM
N2  - The ability of 19 microorganisms to perform the enantioselective lactonization of racemic gamma,delta-epoxy ester 3a and its 7-methyl homolog 3b was checked. It was found that Rhodotorula rubra preferentialy transformed both substrates to (-)-enantiomers of trans delta-hydroxy-gamma-lactones with ee 76 percent for 3a and 24 percent for 3b. The best efficiency (20-30 percent)and enantioselectivity (ee 60-100 percent)of formation of (-)-gamma-hydroxy-delta-lactones 6a and 6b was observed for lactonization by Botrytis cinerea and Fusarium semitectum, respectively
UR  - https://drive.google.com/open?id=1hqan1LskkJmXUxH2Hr8tH6D73akBEddM&usp=drive_copy
ER  -