TY  - BOOK
AU  - Kim,S.
AU  - Kim,J.C.
AU  - Sul,D.
AU  - Hwang,S.W.
AU  - Lee,S.H.
AU  - Kim,Y.H.
AU  - Tae,G.
TI  - Nanoparticle Formulation for Controlled Release of Capsaicin
KW  - CAPSAICIN
KW  - CONTROLLED RELEASE
KW  - PLLA
KW  - NANOPARTICLE
N2  - Capsaicin might be an effective pharmacological agent for the treatment of discogenic back pain due to its effect on pain control neuronal degeneration. Therefore, capsaicin-loaded nano- and micro-particles for sustained release were formulated by nano-precipitation or oil-in-water single emulsion solvent evaporation/extraction method. First, the capsaicin-loaded PLGA nanoparticles were prepared by nano-precipitation method. By increasing the volume of oil-water ratio from 1:2 to 1:5, slight changes in size from 162±3 nm to 153±3 nm and in drug loading efficiency from 25
UR  - https://drive.google.com/file/d/1ZzB4wisNF2L6pDtxN7xl7AqldBaxoWle/view?usp=drivesdk
ER  -