TY  - BOOK
AU  - Mayer,A.
AU  - Anke,H.
AU  - Sterner,O.
TI  - Omphalotin, A New Cyclic Peptide with Potent Nematicidal Activity from Omphalotus Olearius I. Fermentation and Biological Activity
KW  - OMPHALOTUS OLEARIUS
KW  - OMPHALOTIN
KW  - CYCLOPEPTIDE
KW  - 3-(3-INDOLYL)-NMETHYLPROPANAMIDE
KW  - NEMATICIDAL
KW  - MELOIDOGYNE INCOGNITA
KW  - CAENORHABDITIS ELEGANS
N2  - Omphalotin (l), a new cyclic peptide possessing strong and selective nematicidal activity against the plant pathogenic Meloidogyne incognita, was isolated from cultures of the basidiomycete Omphalotus olearius together with the antibiotic sesquiterpene illudin M (2)and the inactive 3-(3-indolyl)-Nmethylpropanamide (3). Omphalotin (1)is only weakly active against the saprophytic nematode Caenorhabditis elegans, it is weakly cytotoxic at 100 pg/ml but shows no phytotoxic, antibacterial or antifungal activities. The fermentation of 0. olearius and the production of the metabolites as well as the evaluation of their biological activities are reported
UR  - https://drive.google.com/file/d/1AB42pLlM4eMoOv00crjXa6Suc8XzY9uv/view?usp=drivesdk
ER  -