Enzymatic hydrolysis of lysine diisocyanate based polyurethanes and segmented polyurethane ureas by various proteases 

 -  Reactive & Functional Polymers, 67(11), p.1338-1345, 2007 .
<br/><br/> This work studies the enzymatic degradation of polyurethanes (PUs)and segmented polyurethane ureas (SPUUs)derived from lysine diisocyanate (LDI)by various proteases. Thiol proteases, such as papain, bromelain, and ficin, showed high activity on PUs. Protease K and chymotrypsin also hydrolyzed the PUs. For almost all SPUUs, apain showed high activity. For example, LDI/poly(caprolactone)diol (Mw = 1250)/ethylene diamine (2/1/1)was hydrolyzed to 43 
<br/><br/><label>Subjects--Topical Terms: </label><br/>POLYURETHANE<br/>BIODEGRADATION<br/>ENZYMATIC HYDROLYSIS<br/>PROTEASE<br/>LYSINE DIISOCYANATE