TY  - BOOK
AU  - Holmquist,L.
AU  - Lewin,M.
TI  - Separation of glutaraldehyde and some of its aldol condensation products by hydroxyl-aldehyde group affinity chromatography
KW  - GLUTARALDEHYDE
KW  - CONDENSATION PRODUCT
KW  - OLIGOMERIC
KW  - POLYMERIC
KW  - SEPARATION
KW  - PARTIAL CHARACTERIZATION
KW  - HYDROXYL-ALDEHYDE GROUP
KW  - INTERACTION CHROMATOGRAPHY
N2  - Glutaraldeh)dc exists in aqueous solution in equilibrium with monomers and polymers of cyclic and open-chain hemialdals and hydrates. At alkaline pH oligomeric and polymeric a,fl-unsaturated aldehyde derivatives are formed from primarily produced aldol condensation products. This communication reports a method for separation of such aldol condensates by means of a new high performance liquid chromatography technique based on the affinity of aldehyde groups for hydroxyl groups of a hydroxylated polyether matrix (Bio-Gel SEC-10). Five peaks corresponding to different aldol condensates of glutaraldehyde were obtained from the affinity column. They have been distinguished by ~tt-NMR and UV spectroscopy. Kinetic measurements yielded formation rates for the different aldol condensates
UR  - https://drive.google.com/file/d/1ONw-8U-l0CTy_suFyU51SeF046_tt9g3/view?usp=drivesdk
ER  -