In vitro degradation of novel medical biodegradable aliphatic polyurethanes based on E-caprolactone and Pluronics1 with various hydrophilicities
- Polymer Degradation and Stability, 75(1), p.113-122, 2002 .
Linear biodegradable polyurethanes with varying ratios of the hydrophilic-to-hydrophobic segment were obtained in the study. The hydrophilic segment was based on poly(ethylene oxide-propylene oxide-ethylene oxide)diols (Pluronic1). The hydrophobic segment was based on poly(E-caprolactone)diol. Viscosity-average molecular weights and the polydispersity index of the polyurethanes were in the range of 38.000-85.000 daltons and 1.2-3.2, respectively. The polymers absorbed up 3.9
POLYURETHANES BIODEGRADABLE PLURONIC IN VITRO DEGRADATION