A time-course study on effects of aluminium on mitotic cell division in Allium sativum
- Mutation Research, 227, p.221-226, 1989 .
Cytotoxic effects of aluminium sulphate on root-tip cells of Allium sativurn during a time-course study and during recovery were observed. The endpoints considered were mitotic index and frequencies of aberrant cells and micronuclei induced. Chronic exposure induced mitotic depression and abnormal ceils to a degree directly proportional to the concentration used and the period of treatment up to 24 h. A reduction of the early higher level of toxicity was noticed following 48 h of treatment and subsequent recovery in aluminiumfree nutrient media in experiments carried out with lower concentrations.