TY  - BOOK
AU  - Albrecht,C.
AU  - Boutrot,F.
AU  - Segonzac,C.
AU  - Schwessinger,B.
AU  - Gimenez-Ibanez,S.
AU  - Chinchilla,D.
AU  - Rathjen,J.P.
AU  - Rathjen,J.P.
AU  - Zipfel,C.
TI  - Brassinosteroids inhibit pathogen-associated molecular pattern-triggered immune signaling independent of the receptor kinase BAK1
KW  - FLAGELLIN SENSING
KW  - BRASSINOSTEROID INSENSITIVE
KW  - BRI
KW  - ASSOCIATED KINASE
KW  - CROSS-TALK
N2  - Plants and animals use innate immunity as a first defense against pathogens, a costly yet necessary tradeoff between growth and immunity. In Arabidopsis, the regulatory leucine-rich repeat receptor- like kinase (LRR-RLK)BAK1 combines with the LRR-RLKs FLS2 and EFR in pathogen-associated molecular pattern (PAMP)-triggered mmunity (PTI)and the LRR-RLK BRI1 in brassinosteroid (BR)- mediated growth. Therefore, a potential tradeoff between these pathways mediated by BAK1 is often postulated. Here, we show a unidirectional inhibition of FLS2-mediated immune signaling by BR perception. Unexpectedly, this effect occurred downstream or ndependently of complex formation with BAK1 and associated downstream phosphorylation. Thus, BAK1 is not rate-limiting in these pathways. BRs also inhibited signaling triggered by the BAK1-independent recognition of the fungal PAMP chitin. Our results suggest a general mechanism operative in plants in which BR-mediated growth directly antagonizes innate immune signaling
UR  - https://drive.google.com/file/d/1DOOX2aI1Ygb72TdKOnkPsEOVJhH_BhF2/view?usp=drivesdk
ER  -