Chaperone-usher pathways: diversity and pilus assembly mechanism
- Phil. Trans. R. Soc., 367(1592), p.1112-1154, 2012 .
Up to eight different types of secretion systems, and several more subtypes, have been described in Gram-negative bacteria. Here, we focus on the diversity and assembly mechanism of one of the beststudied secretion systems, the widespread chaperone-usher pathway known to assemble and secrete adhesive surface structures, called pili or fimbriae, which play essential roles in targeting bacterial pathogens to the host.