Applying systems and synthetic biology approaches to the production of food ingredients, enzymes and nutraceuticals by bacteria - Microbial Production of Food Ingredients, Enzymes and Nutraceuticals, p.81-96, 2013 .

Humans have exploited microorganisms for the production of foodstuffs and food additives for thousands of years. Empirical selection of strains for better or improved production has been a continuous process. Currently molecular biology, genetic engineering, genomics and systems biology are being exploited to speed up the process of selection in a rational fashion. In this chapter I discuss examples of how systems biology and related approaches have been used to inform the production of food-relevant ingredients. The chapter ends with a perspective on how systems biology will continue to develop and become more influential in this area of microbiology


CORYNEBACTERIUM
GENOME SCALE METABOLIC MAPS
METABOLIC ENGINEERING,
NEXT-GENERATION SEQUENCING
SYSTEMS BIOLOGY