Microbial biotransformation as a tool for drug development based on natural products from mevalonic acid pathway: A review
- Journal of Advanced Research, 6(1), p.17-33, 2015 .
Natural products are structurally and biologically interesting metabolites, but they have been isolated in minute amounts. The syntheses of such natural products help in obtaining them in bulk amounts. The recognition of microbial biotransformation as important manufacturing tool has increased in chemical and pharmaceutical industries. In recent years, microbial transformation is increasing significantly from limited interest into highly active area in green chemistry including preparation of pharmaceutical products. This is the first review published on the usage of microbial biocatalysts for some natural product classes and natural product drugs. © 2014
Subjects--Topical Terms: BIOTRANSFORMATION MICROBIAL BIOCATALYSTS NATURAL PRODUCTS PHARMACEUTICAL PRODUCTS