Biology, Genetic Aspects, and Oxidative Stress Response of Streptomyces and Strategies for Bioremediation of Toxic Metals 

 -  Microbial Biodegradation and Bioremediation, p.288-299, 2014 .
<br/><br/> o survive in a metal-contaminated environment, Streptomyces has developed strong regulatory pathways to defend against oxidative stress and detoxify the metal-generated reactive oxygen species combined with intercellular metal-binding and metal-detoxifying mechanisms. The available genomics, transcriptomics, proteomics, and metabolomics data of Streptomyces spp. has further supported the potentiality of this microbe for the purpose of toxic metal bioremediation. Here the genetic role of Streptomyces spp. for oxidative stress and metal-specific regulatory systems is reviewed. And how this knowledge can be used to develop a strategy for the metal bioremediation process is discussed. © 2014 Elsevier Inc. All rights reserved. 
<br/><br/><label>Subjects--Topical Terms: </label><br/>ACTINOBACTERIA; BIOREMEDIATION; OXIDATIVE STRESS; STREPTOMYCES