TY  - BOOK
AU  - Yasumoto,Takeshi
AU  - Seino,Naoko
AU  - Murakami,Yasutaka
AU  - Murata,Michio
TI  - Toxins Produced by Benthic Dinoflagellates
KW  - TOXICITY
KW  - TOXINS
KW  - CIGUATOXINS
KW  - HERBIVOROUS FISHES,CIGUATERA POISONING
KW  - FATTY ACIDS
KW  - CHEMICALS
KW  - JAPANESE CULTURE
KW  - HEMOLYSIN PROTEINS
KW  - MOLECULAR WEIGHT
N2  - Nine species of benthic dinoflagellates collected in subtropical waters were cultured, extracted, and tested for mouse lethality, ichthyotoxicity, and hemolytic activity. Hemolytic activity was detectable in all species, but the activities of Amphidinium carteri, A. k!ebsi, and Gambierdiscus toxicus were outstanding. G. toxicus showed the most potent mouse lethality. Two hemolytic constituents ofA. carteri were deter mined to be mono- and di-galactoglycerolipids. Maitotoxin, produced by G. toxicus, was suggested to have a molecular weight of 3402 ±2 (m/z). Two potent toxins against mice were isolated from Prorocentrum !ima and identified as okadaic acid and 5-methylene-6-hydroxy-2-hexen-l-okadaate
UR  - https://drive.google.com/file/d/1W-Uy_XSq6uF164H6GMt-za3vxcv9z2bS/view?usp=drivesdk
ER  -