TY - BOOK AU - Nielsen,C.B. AU - Cantor,M. AU - Dubchak,I. AU - Gordon,D. AU - Wang,T. TI - Visualizing genomes: Techniques and challenges KW - CHROMATIN ASSEMBLY AND DISASSEMBLY KW - COMPARATIVE GENE MAPPING KW - COMPARATIVE GENOMIC HYBRIDIZATION KW - COMPUTER AIDED DESIGN KW - COMPUTER PROGRAM KW - DATA ANALYSIS KW - GENE EXPRESSION KW - GENE SEQUENCE KW - GENETIC CONSERVATION KW - GENETIC DATABASE KW - GENETIC IDENTIFICATION KW - GENETIC VARIABILITY KW - GENOMICS KW - GENOTYPE KW - HIGH THROUGHPUT SCREENING KW - PRIORITY JOURNAL KW - SEQUENCE ALIGNMENT KW - SEQUENCE ANALYSIS KW - SYNTENY KW - TRANSCRIPTION REGULATION N2 - As our ability to generate sequencing data continues to increase, data analysis is replacing data generation as the rate-limiting step in genomics studies. Here we provide a guide to genomic data visualization tools that facilitate analysis tasks by enabling researchers to explore, interpret and manipulate their data, and in some cases perform on-the-fly computations. We will discuss graphical methods designed for the analysis of de novo sequencing assemblies and read alignments, genome browsing, and comparative genomics, highlighting the strengths and limitations of these approaches and the challenges ahead. © 2010 Nature America, Inc. All rights reserved UR - https://drive.google.com/file/d/1rGhWjVJ_Kxhlb7_Hy2LLy_1ogMhcex_9/view?usp=drivesdk ER -