TY  - BOOK
AU  - Shimatani,Z.
AU  - Kashojiya,S.
AU  - Takayama,M.
AU  - Terada,R.
AU  - Arazoe,T.
AU  - Ishii,H.
AU  - Teramura,H.
AU  - Teramura,H.
AU  - Komatsu,H.
AU  - Miura,K.
AU  - Ezura,H.
AU  - Nishida,K.
AU  - Ariizumi,T.
AU  - Kondo,A.
TI  - Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion
KW  - CROPS
KW  - HERBICIDES
KW  - NUCLEIC ACIDSPLANTS (BOTANY)
KW  - WEED CONTROL
N2  - We applied a fusion of CRISPR-Cas9 and activation-induced cytidine deaminase (Target-AID)for point mutagenesis at genomic regions specified by single guide RNAs (sgRNAs)in two crop plants. In rice, we induced multiple herbicide-resistance point mutations by multiplexed editing using herbicide selection, while in tomato we generated marker-free plants with homozygous heritable DNA substitutions, demonstrating the feasibility of base editing for crop improvement
UR  - https://drive.google.com/file/d/1e_qHU33uJQAVBRBB-QOQ-9czDDygr4W6/view?usp=drivesdk
ER  -